Saturday, November 7

By Abayomi Ajayi

Egg freezing, medically known as oocyte cryopreservation, allows you to preserve some of your eggs at their current biological age for potential use in the future. This gives you an opportunity to postpone pregnancy without relying entirely on the eggs your ovaries will produce years later.

But there is an important distinction: freezing your eggs does not stop your biological clock. It preserves the eggs at the age they were retrieved; your body continues to age, and your chances of conceiving naturally may still decline. The technology offers some protection against age-related deterioration in egg quality, not a guarantee of motherhood.

One of the first things you need to understand is that your age at the time of egg retrieval matters considerably more than your age when you eventually decide to use them.

You are born with a finite supply of eggs; unlike sperm production in men, which continues throughout much of adult life, the number of eggs available to you declines over time. Their quality also changes as you age.

However, it does not mean that freezing your eggs at 30 guarantees a successful pregnancy at 42. The number of eggs retrieved, their survival after thawing, fertilisation rates and embryo development all influence the eventual outcome.

The difference between freezing your eggs at 30 and waiting until 39 can be significant. By the late 30s, ovarian reserve and egg quality may have declined considerably. You may therefore need more treatment cycles to collect an adequate number of mature eggs.

But age is only part of the equation. The quality of your eggs matters, and having a large number does not necessarily guarantee your chances of having a child.

Imagine retrieving 15 eggs during a stimulation cycle. It may sound reassuring, but the number alone cannot tell you how many will eventually produce a baby.

Some retrieved eggs may not be mature enough to freeze; others may not survive thawing. Even among those that survive, not all will fertilise successfully or develop into embryos suitable for transfer.

Egg quality is particularly important because it influences the likelihood of normal fertilisation and embryo development. One major concern is aneuploidy, a condition in which an egg or embryo has an abnormal number of chromosomes.

The likelihood of this increases with maternal age and is one reason pregnancy rates decline and miscarriage risks rise as women get older.

If you freeze 15 mature eggs at 30, for instance, your reproductive outlook may be different from that of another woman who freezes the same number at 39.

Although both of you have preserved 15 eggs, the likelihood that those eggs will produce chromosomally normal embryos may differ. Your ovarian reserve also matters.

However, the tests do not directly measure egg quality or predict with certainty whether you will eventually have a baby. Your age remains a major indicator of egg quality.

The point is that egg freezing should not become a numbers game. Collecting more eggs can improve your cumulative chances of a live birth, but the age and biological quality of those eggs remain critical. Another question you may have is how long frozen eggs can remain usable.

If you freeze your eggs at 32 and decide to use them at 42 or even 45, will they still be capable of producing a pregnancy?

Modern egg-freezing technology can preserve eggs for extended periods without the usual biological ageing that occurs inside the body.

Most fertility centres use a technique called vitrification, an ultra-rapid freezing method that prevents the formation of damaging ice crystals within the egg. Once vitrified and stored under appropriate conditions in liquid nitrogen, your eggs remain at extremely low temperatures, effectively suspending their biological activity.

In practical terms, an egg frozen at 30 does not become biologically 40 simply because it has spent a decade in storage. Its biological age remains the age at retrieval. The age of your eggs when frozen is a major determinant of their reproductive potential, while your age when you eventually carry the pregnancy introduces separate considerations.

For example, if you use eggs frozen at 31 when you are 43, you may benefit from the younger biological age of those eggs; however, you will still be 43, and your general health, uterine condition and ability to safely carry a pregnancy must be assessed.

Freezing your eggs may preserve an important part of your reproductive potential, but it does not freeze your entire reproductive system.

Freezing eggs in the early 30s may have a better chance of achieving a live birth from a given number of eggs than someone freezing the same number in her late 30s.

Not every egg will survive thawing, fertilise successfully or develop into an embryo suitable for transfer. This is why you may need more than one stimulation and retrieval cycle, particularly if you begin the process at an older age or produce relatively few mature eggs.

It is equally important to understand that freezing your eggs is only the first stage of the journey. When you eventually decide to use them, another process begins. For many Nigerian women, the decision to freeze eggs involves more than medical considerations. It also involves affordability, consultations, fertility assessments, hormonal medication, egg retrieval, laboratory procedures and ongoing storage fees.

So, can frozen eggs really beat the biological clock? If you mean stopping your reproductive system from ageing, egg freezing cannot do that. Your ovarian reserve will continue to decline, and your body will continue to age. If, however, you mean preserving eggs at a younger biological age for possible use later, then the technology offers a genuine opportunity, within limits.

Ultimately, motherhood does not have to follow a single timetable. You may not be ready for a child today, but you may want that possibility in the future. Egg freezing cannot promise that future. What it can offer is a chance to preserve some of your younger eggs, giving you another option when the time feels right.

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